Certified Safety Professional Practice Exam

The feature that provides the highest level of worker protection in biosafety labs is gas-tight, negative pressure systems. These systems ensure that any potentially harmful aerosols or contaminants created during laboratory work are contained within the lab environment. The negative pressure helps prevent the escape of airborne pathogens, as the air flows inward from surrounding areas, effectively minimizing the risk of exposure to laboratory personnel and the outside environment.

In contrast, an open lab layout can increase the likelihood of exposure to biohazardous materials by allowing unrestricted airflow and movement throughout the space, which diminishes the containment effectiveness. Recycling air systems may create a more comfortable lab environment, but they can also circulate potential contaminants rather than containing them. Basic containment practices are essential but do not offer the robust protection provided by gas-tight, negative pressure systems, which are specifically designed to handle hazardous materials safely.